DNAM-1 (phospho Ser329) Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], function:Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell., PTM:Phosphorylated., similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with PVR and PVRL2., tissue specificity:Expressed by peripheral blood T-lymphocytes.
Product Name Alternative
CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD antigen CD226
Gene Name
CD226
Gene ID
10666
Swiss Prot
Q15762
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Cell adhesion molecules (CAMs)
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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