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EF-2 Rabbit Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008], function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome., PTM:Diphthamide is 2-[3-carboxyamido-3- (trimethyl-ammonio) propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A., PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2., similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily., subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.

Product Name Alternative

EEF2; EF2; Elongation factor 2; EF-2

Gene Name

EEF2

Gene ID

1938

Swiss Prot

P13639

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Field of Research

AMPK

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:10000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

100kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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