NK-3R Rabbit Polyclonal Antibody

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008], function:This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B) . It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system., miscellaneous:The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P., PTM:The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue., similarity:Belongs to the G-protein coupled receptor 1 family.