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RGS16 Rabbit Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008], function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G (i) -alpha and G (o) -alpha, but not to G (s) -alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade., PTM:Palmitoylated on Cys-2 and/or Cys-12., PTM:Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G (i) -alpha., similarity:Contains 1 RGS domain., tissue specificity:Abundantly expressed in retina with lower levels of expression in most other tissues.

Product Name Alternative

RGS16; RGSR; Regulator of G-protein signaling 16; RGS16; A28-RGS14P; Retinal-specific RGS; RGS-r; hRGS-r; Retinally abundant regulator of G-protein signaling

Gene Name

RGS16

Gene ID

6004

Swiss Prot

O15492

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Purification

Affinity purification

Dilution

IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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