SCP-3 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010], disease:Defects in SYCP3 are associated with azoospermia due to perturbations of meiosis [MIM:270960]., function:Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development., similarity:Belongs to the XLR/SYCP3 family., subcellular location:In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed., subunit:Interacts with SYCP2., tissue specificity:Testis-specific.
Product Name Alternative
SYCP3; SCP3; Synaptonemal complex protein 3; SCP-3
Gene Name
SYCP3
Gene ID
50511
Swiss Prot
Q8IZU3
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
27kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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