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SNM1B Rabbit Polyclonal Antibody

Product Specifications

Background

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]) .[supplied by OMIM, Mar 2008], function:May be required for DNA interstrand cross-link repair., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family., subcellular location:Localizes to discrete foci.

Product Name Alternative

DCLRE1B; SNM1B; 5' exonuclease Apollo; DNA cross-link repair 1B protein; SNM1 homolog B; SNMIB; hSNM1B

Gene Name

DCLRE1B

Gene ID

64858

Swiss Prot

Q9H816

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

60kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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