MPP10 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010], function:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) . Required for the early cleavages during pre-18S ribosomal RNA processing., PTM:Phosphorylated in M (mitotic) phase., similarity:Belongs to the MPP10 family., subcellular location:Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin., subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with IMP3 and IMP4.
Product Name Alternative
MPHOSPH10; MPP10; U3 small nucleolar ribonucleoprotein protein MPP10; M phase phosphoprotein 10
Gene Name
MPHOSPH10
Gene ID
10199
Swiss Prot
O00566
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
78kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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