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MGST2 Rabbit Polyclonal Antibody

Product Specifications

Background

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011], catalytic activity:RX + glutathione = HX + R-S-glutathione., function:Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione., similarity:Belongs to the MAPEG family., subunit:Homotrimer., tissue specificity:Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow.

Product Name Alternative

MGST2; GST2; Microsomal glutathione S-transferase 2; Microsomal GST-2; Microsomal GST-II

Gene Name

MGST2

Gene ID

4258

Swiss Prot

Q99735

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA

Field of Research

Glutathione metabolism; Metabolism of xenobiotics by cytochrome P450; Drug metabolism

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

17kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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