Galectin-7 Rabbit Polyclonal Antibody

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008], function:Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release., induction:By p53., online information:Galectin-7, similarity:Contains 1 galectin domain., subcellular location:May be secreted by a non-classical secretory pathway., subunit:Monomer., tissue specificity:Mainly in stratified squamous epithelium.