T2R50 Rabbit Polyclonal Antibody
Product Specifications
Background
TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]) . See also TAS2R10 (MIM 604791) .[supplied by OMIM, Mar 2008], function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5., miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli., similarity:Belongs to the G-protein coupled receptor T2R family., tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Gene Name
TAS2R50
Gene ID
259296
Swiss Prot
P59544
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Taste transduction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
32kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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