SL9C1 Rabbit Polyclonal Antibody

SLC9A10 is a member of the sodium-hydrogen exchanger (NHE) family (see SLC9A1, MIM 107310) and is required for male fertility and sperm motility (Wang et al., 2003 [PubMed 14634667]) .[supplied by OMIM, Apr 2009], domain:The ion transport-like region is related to the membrane segments of voltage-gated ion channels. Its function is unknown., function:Sperm-specific sodium/hydrogen exchanger involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC) ., similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family., similarity:Contains 1 cyclic nucleotide-binding domain., subunit:Interacts with soluble adenylyl cyclase (sAC) .