MIXL1 Rabbit Polyclonal Antibody
Product Specifications
Background
Mix paired-like homeobox (MIXL1) Homo sapiens Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]) .[supplied by OMIM, Mar 2008], function:Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression., PTM:Phosphorylated at multiple sites., similarity:Belongs to the paired homeobox family., similarity:Contains 1 homeobox DNA-binding domain., tissue specificity:Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B-and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level) .
Gene Name
MIXL1 MIXL
Gene ID
83881
Swiss Prot
Q9H2W2
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
25kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/APRab13922_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
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