MAZ Rabbit Polyclonal Antibody

Function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors., similarity:Contains 6 C2H2-type zinc fingers., subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures., subunit:Interacts with BPTF., tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level) ., function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors., similarity:Contains 6 C2H2-type zinc fingers., subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures., subunit:Interacts with BPTF., tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level) .

MAZ; ZNF801; Myc-associated zinc finger protein; MAZI; Pur-1; Purine-binding transcription factor; Transcription factor Zif87; ZF87; Zinc finger protein 801