RO60 Rabbit Polyclonal Antibody

Disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign., function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the Ro 60 kDa family., similarity:Contains 1 TROVE domain., subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11., disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign., function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the Ro 60 kDa family., similarity:Contains 1 TROVE domain., subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.

TROVE2; RO60; SSA2; 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; RoRNP; Ro 60 kDa autoantigen; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; SS-A; TROVE domain family member 2