Neuronal PAS1 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) -PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008], function:May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., similarity:Contains 1 PAC (PAS-associated C-terminal) domain., similarity:Contains 2 PAS (PER-ARNT-SIM) domains., subunit:Efficient DNA binding requires dimerization with another bHLH protein. Interacts with ARNT.
Product Name Alternative
NPAS1; BHLHE11; MOP5; PASD5; Neuronal PAS domain-containing protein 1; Neuronal PAS1; Basic-helix-loop-helix-PAS protein MOP5; Class E basic helix-loop-helix protein 11; bHLHe11; Member of PAS protein 5; PAS domain-containing protein 5
Gene Name
NPAS1
Gene ID
4861
Swiss Prot
Q99742
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
62kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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