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PI 3 Kinase Class 3 Rabbit Polyclonal Antibody

Product Specifications

Background

Catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate., cofactor:Manganese., function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes., similarity:Belongs to the PI3/PI4-kinase family., similarity:Contains 1 PI3K/PI4K domain., subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity) . Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4., tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle., catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate., cofactor:Manganese., function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes., similarity:Belongs to the PI3/PI4-kinase family., similarity:Contains 1 PI3K/PI4K domain., subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity) . Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4., tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle.

Product Name Alternative

Phosphoinositide-3-kinase, class 3

Gene Name

PIK3C3 VPS34

Gene ID

5289

Swiss Prot

Q8NEB9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC

Field of Research

Inositol phosphate metabolism; Phosphatidylinositol signaling system; Regulation of autophagy

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:50-1:300

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

100kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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