SPHK1 (Phospho-Ser225) Rabbit Polyclonal Antibody
Product Specifications
Background
Catalytic activity:ATP + sphinganine = ADP + sphinganine 1-phosphate., catalytic activity:ATP + sphingosine = ADP + sphingosine 1-phosphate., cofactor:Magnesium., function:Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D, L-threo-dihydrosphingosine, N, N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol., similarity:Contains 1 DAGKc domain., subunit:Interacts with ACY1 (By similarity) . Binds to calmodulin. Interacts with SPHKAP., tissue specificity:Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
Product Name Alternative
Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)
Gene Name
SPHK1 SPHK SPK
Gene ID
8877
Swiss Prot
Q9NYA1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Purification
Affinity purification
Dilution
WB 1:500-1:2000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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