GSTK1 Rabbit Polyclonal Antibody

This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009], catalytic activity:RX + glutathione = HX + R-S-glutathione., function:Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB) ., similarity:Belongs to the GST superfamily. Kappa family., subunit:Homodimer., tissue specificity:Ubiquitous.