Ran BP-17 Rabbit Polyclonal Antibody
Product Specifications
Background
RAN binding protein 17 (RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002], function:May function as a nuclear transport receptor., similarity:Belongs to the exportin family., subunit:Binds to nucleoporins and the GTP-bound form of Ran., tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.
Product Name Alternative
RANBP17; Ran-binding protein 17
Gene Name
RANBP17
Gene ID
64901
Swiss Prot
Q9H2T7
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
125kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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