DGK-ε Rabbit Polyclonal Antibody

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008], catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate., function:Highly selective for arachidonate-containing species of diacylglycerol (DAG) . May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition., similarity:Belongs to the eukaryotic diacylglycerol kinase family., similarity:Contains 1 DAGKc domain., similarity:Contains 2 phorbol-ester/DAG-type zinc fingers., tissue specificity:Expressed predominantly in testis.