DZIP3 Rabbit Polyclonal Antibody
Product Specifications
Background
Function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA., pathway:Protein modification; protein ubiquitination., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Contains 1 RING-type zinc finger., subunit:Interacts with DAZ proteins., tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas., function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA., pathway:Protein modification; protein ubiquitination., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Contains 1 RING-type zinc finger., subunit:Interacts with DAZ proteins., tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
Product Name Alternative
DZIP3; KIAA0675; E3 ubiquitin-protein ligase DZIP3; DAZ-interacting protein 3; RNA-binding ubiquitin ligase of 138 kDa; hRUL138
Gene Name
DZIP3
Gene ID
9666
Swiss Prot
Q86Y13
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
140kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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