TWIK-1 Rabbit Polyclonal Antibody

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008], function:Weakly inward rectifying potassium channel., miscellaneous:Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C., similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family., subunit:Homodimer ., tissue specificity:Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney.