FKBPL Rabbit Polyclonal Antibody

The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008], function:May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 3 TPR repeats., subunit:Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90., tissue specificity:Ubiquitously expressed with higher levels in testis.