GABAA Rε Rabbit Polyclonal Antibody
Product Specifications
Background
The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008], function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel., similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family., subunit:Generally pentameric. Associates with alpha and beta subunits., tissue specificity:Expressed in many tissues. Highest levels of expression in adult heart and placenta.
Product Name Alternative
GABRE; Gamma-aminobutyric acid receptor subunit epsilon; GABA (A) receptor subunit epsilon
Gene Name
GABRE
Gene ID
2564
Swiss Prot
P78334
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Neuroactive ligand-receptor interaction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
57kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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