CD28 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011], function:Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival., online information:CD28 entry, similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70., tissue specificity:Expressed in T-cells and plasma cells, but not in less mature B-cells.
Product Name Alternative
CD28; T-cell-specific surface glycoprotein CD28; TP44; CD28
Gene Name
CD28
Gene ID
940
Swiss Prot
P10747
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Cell adhesion molecules (CAMs) ; T_Cell_Receptor; Intestinal immune network for IgA production; Type I diabetes mellitus; Autoimmune thyroid disease; Systemic lupus erythematosus; Allograft rejection; Graft-versus-host disease; Viral myocarditis
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
25kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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