CD272 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011], function:Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response., PTM:N-glycosylated., PTM:Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Interacts with TNFRSF14/HVEM.
Product Name Alternative
BTLA; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD antigen CD272
Gene Name
BTLA
Gene ID
151888
Swiss Prot
Q7Z6A9
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, FC
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
36kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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