SSTR2 Rabbit Polyclonal Antibody
Product Specifications
Background
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008], function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels., similarity:Belongs to the G-protein coupled receptor 1 family., subunit:The C-terminus interacts with SHANK1 PDZ domain., tissue specificity:Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.
Product Name Alternative
Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)
Gene Name
SSTR2
Gene ID
6752
Swiss Prot
P30874
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Neuroactive ligand-receptor interaction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
40kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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