ABCF1 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008], function:May function in mRNA translation., induction:By TNF (in cultured synoviocytes) ., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the ABC transporter family., similarity:Belongs to the ABC transporter family. EF3 subfamily., similarity:Contains 2 ABC transporter domains., subunit:Interacts with eukaryotic initiation factor 2 (eIF2) . Associates with the ribosomes., tissue specificity:Ubiquitous.
Product Name Alternative
ABCF1; ABC50; ATP-binding cassette sub-family F member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein
Gene Name
ABCF1
Gene ID
23
Swiss Prot
Q8NE71
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
95kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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