SAMHD1 (phospho-Thr592) Rabbit Polyclonal Antibody
Product Specifications
Background
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010], function:May play a role in mediating proinflammatory responses to TNF-alpha signaling., induction:By interferon gamma. Up-regulated in TNF-alpha treated lung fibroblasts., similarity:Contains 1 HD domain., similarity:Contains 1 SAM (sterile alpha motif) domain., tissue specificity:Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.
Product Name Alternative
SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)
Gene Name
SAMHD1 MOP5
Gene ID
25939
Swiss Prot
Q9Y3Z3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Purification
Affinity purification
Dilution
WB 1:1000-1:2000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
72kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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