CHD6 Rabbit Polyclonal Antibody

This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013], function:Probable transcription regulator., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:The sequence differs from position 1528 onward for unknown reasons., similarity:Belongs to the SNF2/RAD54 helicase family., similarity:Contains 1 helicase ATP-binding domain., similarity:Contains 1 helicase C-terminal domain., similarity:Contains 2 chromo domains., tissue specificity:Ubiquitous.