CD80 Rabbit Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011], function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses., tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.

Product Name Alternative

T-lymphocyte activation antigen CD80 (Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80)

Gene Name

CD80 CD28LG CD28LG1 LAB7

Gene ID

941

Swiss Prot

P33681

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Field of Research

Cell adhesion molecules (CAMs) ; Toll_Like; Intestinal immune network for IgA production; Type I diabetes mellitus; Autoimmune thyroid disease; Systemic lupus erythematosus; Allograft rejection; Graft-versus-host disease; Viral myocarditis