CD80 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011], function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses., tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.
Product Name Alternative
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80)
Gene Name
CD80 CD28LG CD28LG1 LAB7
Gene ID
941
Swiss Prot
P33681
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Field of Research
Cell adhesion molecules (CAMs) ; Toll_Like; Intestinal immune network for IgA production; Type I diabetes mellitus; Autoimmune thyroid disease; Systemic lupus erythematosus; Allograft rejection; Graft-versus-host disease; Viral myocarditis
Purification
Affinity purification
Dilution
IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/APRab08462_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
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