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AVP Receptor V3 Rabbit Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008], function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system., similarity:Belongs to the G-protein coupled receptor 1 family.

Product Name Alternative

Vasopressin V1b receptor (V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor)

Gene Name

AVPR1B AVPR3 VPR3

Gene ID

553

Swiss Prot

P47901

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Field of Research

Calcium; Neuroactive ligand-receptor interaction; Vascular smooth muscle contraction

Purification

Affinity purification

Dilution

IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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