MYCNOS Rabbit Polyclonal Antibody

This gene is transcribed in antisense to the v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog gene (MYCN) . It is thought to encode a small, novel protein that stabilizes MYCN, prevents apoptosis, and promotes cell proliferation. Transcripts at this locus may also act directly as functional RNAs to recruit transcriptional regulators to the promoter of MYCN and stimulate transcription of this oncogene. This gene therefore functions through both RNA and protein products. [provided by RefSeq, Aug 2016], developmental stage:Expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels., function:May have a functional role during normal fetal development., tissue specificity:Expressed in the fetal brain, lung, liver and kidney at varying low levels.