ARHGAP23 Rabbit Polyclonal Antibody
Product Specifications
Background
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]) .[supplied by OMIM, Mar 2008], function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 PH domain., similarity:Contains 1 Rho-GAP domain., tissue specificity:Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor.
Product Name Alternative
ARHGAP23; KIAA1501; Rho GTPase-activating protein 23; Rho-type GTPase-activating protein 23
Gene Name
ARHGAP23
Gene ID
57636
Swiss Prot
Q9P227
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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