β-1,4-GalNAc-T Rabbit Polyclonal Antibody
Product Specifications
Background
Catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl- (1->3) -D-galactosyl-proteoglycan = UDP + N-acetyl-D-galactosaminyl- (1->4) -beta-D-glucuronyl- (1->3) -beta-D-galactosylproteoglycan., function:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA) . Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage., online information:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1, online information:GlycoGene database, PTM:N-glycosylated., similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family., tissue specificity:Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined., catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl- (1->3) -D-galactosyl-proteoglycan = UDP + N-acetyl-D-galactosaminyl- (1->4) -beta-D-glucuronyl- (1->3) -beta-D-galactosylproteoglycan., function:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA) . Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage., online information:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1, online information:GlycoGene database, PTM:N-glycosylated., similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family., tissue specificity:Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined.
Product Name Alternative
CSGALNACT1; CHGN; GALNACT1; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CsGalNAcT-1; Chondroitin beta-1; 4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1
Gene Name
CSGALNACT1
Gene ID
55790
Swiss Prot
Q8TDX6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Chondroitin sulfate biosynthesis
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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