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UBE2G1 Rabbit Polyclonal Antibody

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008], catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine., function:Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in degradation of muscle-specific proteins., pathway:Protein modification; protein ubiquitination., similarity:Belongs to the ubiquitin-conjugating enzyme family., tissue specificity:Widely expressed, mainly in skeletal muscle.

Product Name Alternative

UBE2G1; UBE2G; Ubiquitin-conjugating enzyme E2 G1; E217K; UBC7; Ubiquitin carrier protein G1; Ubiquitin-protein ligase G1

Gene Name

UBE2G1

Gene ID

7326

Swiss Prot

P62253

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Field of Research

Ubiquitin mediated proteolysis; Parkinson's disease

Purification

Affinity purification

Dilution

IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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