Neuron Navigator 1 Rabbit Polyclonal Antibody

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009], developmental stage:Expressed in fetal brain and heart., function:May be involved in neuronal migration., similarity:Belongs to the Nav/unc-53 family., subcellular location:Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones., subunit:Interacts with tubulin., tissue specificity:Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.

NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1; Neuron navigator 1; Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1