APC1 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011], function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis., similarity:Belongs to the APC1 family., similarity:Contains 4 PC repeats., subunit:The APC/C is composed of at least 11 subunits.
Product Name Alternative
ANAPC1; TSG24; Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein
Gene Name
ANAPC1
Gene ID
64682
Swiss Prot
Q9H1A4
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Field of Research
Cell_Cycle_G1S; Cell_Cycle_G2M_DNA; Oocyte meiosis; Ubiquitin mediated proteolysis; Progesterone-mediated oocyte maturation
Purification
Affinity purification
Dilution
IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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