TSSK 6 Rabbit Polyclonal Antibody

This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012], catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family., similarity:Contains 1 protein kinase domain., subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity., tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.

TSSK6; SSTK; FKSG82; Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK-6; Testis-specific kinase 6; Cancer/testis antigen 72; CT72; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase