CDK5 Activator-binding C42 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013], cofactor:Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine., function:Specifically inhibits CDK5 activation by CDK5R1., sequence caution:Translated as Glu., similarity:Belongs to the methylthiotransferase family. MiaB subfamily., similarity:Contains 1 MTTase N-terminal domain., similarity:Contains 1 TRAM domain., subunit:Interacts with CDK5R1 (p35 form) . CDK5RAP1, CDK5RAP2 and CDK5RAP3 show competitive binding to CDK5R1. Forms a complex with CDK5R1 and CDK5., tissue specificity:Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Product Name Alternative
CDK5RAP1; C20orf34; CGI-05; HSPC167; CDK5 regulatory subunit-associated protein 1; CDK5 activator-binding protein C42
Gene Name
CDK5RAP1
Gene ID
51654
Swiss Prot
Q96SZ6
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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