NPAS4 Rabbit Polyclonal Antibody
Product Specifications
Background
NXF is a member of the basic helix-loop-helix-PER (MIM 602260) -ARNT (MIM 126110) -SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]) .[supplied by OMIM, Mar 2008], function:Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., similarity:Contains 1 PAC (PAS-associated C-terminal) domain., similarity:Contains 2 PAS (PER-ARNT-SIM) domains., subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT., tissue specificity:Brain.
Product Name Alternative
NPAS4; BHLHE79; NXF; PASD10; Neuronal PAS domain-containing protein 4; Neuronal PAS4; Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10
Gene Name
NPAS4
Gene ID
266743
Swiss Prot
Q8IUM7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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