NPAS4 Rabbit Polyclonal Antibody

NXF is a member of the basic helix-loop-helix-PER (MIM 602260) -ARNT (MIM 126110) -SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]) .[supplied by OMIM, Mar 2008], function:Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., similarity:Contains 1 PAC (PAS-associated C-terminal) domain., similarity:Contains 2 PAS (PER-ARNT-SIM) domains., subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT., tissue specificity:Brain.

NPAS4; BHLHE79; NXF; PASD10; Neuronal PAS domain-containing protein 4; Neuronal PAS4; Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10