CD164 Rabbit Polyclonal Antibody

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]) .[supplied by OMIM, Aug 2008], function:This is a carcinoma-associated protein, probably a mucin., PTM:Highly N- and O-glycosylated; contains sialic acid., PTM:The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain., similarity:Belongs to the CD164 family., tissue specificity:Small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma.