MOF Rabbit Polyclonal Antibody

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012], catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone., function:Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM., similarity:Belongs to the MYST (SAS/MOZ) family., similarity:Contains 1 C2HC-type zinc finger., similarity:Contains 1 chromo domain., subunit:Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/MYST1, MSL1/hampin, MSL2L1 and MSL3L1. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain.