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GCS-β-2 Rabbit Polyclonal Antibody

Product Specifications

Background

Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Product Name Alternative

GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2

Gene Name

GUCY1B2

Gene ID

2974

Swiss Prot

O75343

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Purification

Affinity purification

Dilution

IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

70kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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