ZHX2 Rabbit Polyclonal Antibody

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008], function:Acts as a transcriptional repressor., similarity:Belongs to the ZHX family., similarity:Contains 2 C2H2-type zinc fingers., similarity:Contains 4 homeobox DNA-binding domains., subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA., tissue specificity:Ubiquitously expressed.

ZHX2; AFR1; KIAA0854; RAF; Zinc fingers and homeoboxes protein 2; Alpha-fetoprotein regulator 1; AFP regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2