USP24 Rabbit Polyclonal Antibody
Product Specifications
Background
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]) .[supplied by OMIM, Mar 2008], catalytic activity:Ubiquitin C-terminal thioester + H (2) O = ubiquitin + a thiol., function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the peptidase C19 family., similarity:Contains 1 UBA domain.
Product Name Alternative
USP24; KIAA1057; Ubiquitin carboxyl-terminal hydrolase 24; Deubiquitinating enzyme 24; Ubiquitin thioesterase 24; Ubiquitin-specific-processing protease 24
Gene Name
USP24
Gene ID
23358
Swiss Prot
Q9UPU5
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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