CELSR3 Rabbit Polyclonal Antibody

This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013], function:Does not seem to be involved in anion transport., function:Receptor that may have an important role in cell/cell signaling during nervous system formation., similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily., similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family., similarity:Contains 1 GPS domain., similarity:Contains 1 laminin EGF-like domain., similarity:Contains 1 STAS domain., similarity:Contains 2 laminin G-like domains., similarity:Contains 8 EGF-like domains., similarity:Contains 9 cadherin domains., tissue specificity:Ubiquitous. Highest levels in kidney and pancreas. Lower expression in heart, skeletal muscle, liver and placenta. Also found in lung and brain.

CELSR3; CDHF11; EGFL1; FMI1; KIAA0812; MEGF2; Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; Epidermal growth factor-like protein 1; EGF-like protein 1; Flamingo homolog 1; hFmi1; Multiple epidermal growth factor-