FPR1 Rabbit Polyclonal Antibody

Formyl peptide receptor 1 (FPR1) Homo sapiens This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010], function:High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system., PTM:Phosphorylated; which is necessary for desensitization., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Neutrophils.